The 123I-mIBG heart/mediastinum ratio: Moving from 2D to 3D imaging
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چکیده
منابع مشابه
Myocardial iodine-123-metaiodobenzylguanidine (123I-MIBG) imaging in Brugada syndrome.
(I-MIBG) Imaging in Brugada Syndrome To the Editor: We read with interest a recent article in Circulation by Wichter et al1 on cardiac autonomic dysfunction in Brugada syndrome. The authors demonstrated that regionally reduced iodine-123-metaiodobenzylguanidine (I-MIBG) uptake in the inferior and septal left ventricular wall was present in 8 (47%) of 17 patients with Brugada syndrome but in non...
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Up to the end of the 70’s, Medical Imaging was mainly related to the study of planar data sets resulting from direct physical acquisitions (e.g. X-Ray radiographs). Then, the development of inverse methods associated with the increasing power of computers enabled the visualization and the analysis of human being cross-section images (e.g. CT scans, MRI): these images are the result of mathemati...
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Objective(s): Iodine-123 metaiodobenzylguanidine (123I-MIBG) myocardial scintigraphy has been used to evaluate cardiac sympathetic denervation in Lewy body disease (LBD), including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). The heart-tomediastinum ratio (H/M) in PD and DLB is significantly lower than that in Parkinson’s plus syndromes and Alzheimer’s disease. Although this ra...
متن کاملImaging the norepinephrine transporter in neuroblastoma: a comparison of [18F]-MFBG and 123I-MIBG.
PURPOSE The norepinephrine transporter (NET) is a critical regulator of catecholamine uptake in normal physiology and is expressed in neuroendocrine tumors like neuroblastoma. Although the norepinephrine analog, meta-iodobenzylguanidine (MIBG), is an established substrate for NET, (123)I/(131)I-MIBG has several clinical limitations for diagnostic imaging. In the current studies, we evaluated me...
متن کاملCardiac autonomic neuropathy in the diabetic patient: does 123I-MIBG imaging have a role to play in early diagnosis?
OBJECTIVES In diabetes, extended adrenergic receptor stimulation with hyperglycemia and insulin deficiency is associated with cardiac autonomic dysfunction. Clinically evident diabetic cardiac autonomic neuropathy (CAN) is associated with a poor prognosis. Research studies indicate that autonomic function tests, which are traditionally used to diagnose diabetic CAN, are less sensitive than (123...
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ژورنال
عنوان ژورنال: Journal of Nuclear Cardiology
سال: 2020
ISSN: 1071-3581,1532-6551
DOI: 10.1007/s12350-020-02106-3